Application of microextraction by packed sorbent to isolation of psychotropic drugs from human serum

Abstract

A method of microextraction by packed sorbent (MEPS) followed by liquid chromatography with diode array detection has been developed and optimized for the extraction of six tricyclic antidepressants (amitriptyline, nortriptyline, imipramine, desipramine, doxepin, nordoxepin) from human serum. The optimal parameters of MEPS extraction (type of sorbent… (More)
DOI: 10.1007/s00216-011-5442-0

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