Application of microarrays for DNA methylation profiling.

  title={Application of microarrays for DNA methylation profiling.},
  author={Axel Schumacher and Andreas Weinh{\"a}usl and Artūras Petronis},
  journal={Methods in molecular biology},
Comprehensive analyses of the human epigenome may be of critical importance in understanding the molecular mechanisms of complex diseases, development, aging, tissue specificity, parental origin effects, and sex differences, among other systemic aspects of human biology. However, traditional DNA methylation methods allowed for screening of only relatively short DNA fragments. The advent of microarrays has provided new possibilities in DNA methylation analysis, because this technology is able to… CONTINUE READING

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