Application of matrix-assisted laser desorption ionization time-of-flight mass spectrometry to the analysis of glycopeptide-containing multiple O-linked oligosaccharides.

@article{Iwase1998ApplicationOM,
  title={Application of matrix-assisted laser desorption ionization time-of-flight mass spectrometry to the analysis of glycopeptide-containing multiple O-linked oligosaccharides.},
  author={Hitoo Iwase and Akiko Tanaka and Yoshiyuki Hiki and Tohru Kokubo and Ikuko Ishii-Karakasa and Joji Nishikido and Yutaka Kobayashi and Kinya Hotta},
  journal={Journal of chromatography. B, Biomedical sciences and applications},
  year={1998},
  volume={709 1},
  pages={145-9}
}
In our previous report [Iwase et al., J. Biochem., 120 (1996) 393], the number of O-linked oligosaccharide chains on the hinge region of IgA1 was estimated by matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOFMS). In this experiment, the number of non-substituted N-acetylgalactosamines and Galbeta1,3GalNAc residues, as the core O-linked oligosaccharide structure per heavy chain of normal human serum IgA1, was estimated by digestion of the asialo-hinge… CONTINUE READING

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