Application of magnetic resonance (MR) imaging for the development and validation of computational fluid dynamic (CFD) models of the rat respiratory system.

@article{Minard2006ApplicationOM,
  title={Application of magnetic resonance (MR) imaging for the development and validation of computational fluid dynamic (CFD) models of the rat respiratory system.},
  author={Kevin R. Minard and Daniel R. Einstein and Richard E. Jacob and Senthil Kabilan and Andrew P. Kuprat and Charles A Timchalk and Lynn Trease and Richard A. Corley},
  journal={Inhalation toxicology},
  year={2006},
  volume={18 10},
  pages={787-94}
}
Computational fluid dynamic (CFD) models of the respiratory system provide a quantitative basis for extrapolating the localized dose of inhaled materials and improving human health risk assessments based upon inhalation studies conducted in animals. Nevertheless, model development and validation have historically been tedious and time-consuming tasks. In recognition of this, we previously reported on the use of proton (1H) magnetic resonance (MR) imaging for visualizing nasal-sinus passages in… CONTINUE READING

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