Application of human mesenchymal and pluripotent stem cell microcarrier cultures in cellular therapy: achievements and future direction.

@article{Chen2013ApplicationOH,
  title={Application of human mesenchymal and pluripotent stem cell microcarrier cultures in cellular therapy: achievements and future direction.},
  author={Allen Kuan-Liang Chen and Shaul Reuveny and Steve Kah-Weng Oh},
  journal={Biotechnology advances},
  year={2013},
  volume={31 7},
  pages={1032-46}
}
Mesenchymal stem cells (MSCs) have recently made significant progress with multiple clinical trials targeting modulation of immune responses, regeneration of bone, cartilage, myocardia, and diseases like Metachromatic leukodystrophy and Hurler syndrome. On the other hand, the use of human embryonic and induced pluripotent stem cells (hPSCs) in clinical trials is rather limited mainly due to safety issues. Only two clinical trials, retinal pigment epithelial transplantation and treatment of… CONTINUE READING

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