Application of headspace solid phase microextraction to qualitative and quantitative analysis of tobacco additives in cigarettes.

@article{Merckel2006ApplicationOH,
  title={Application of headspace solid phase microextraction to qualitative and quantitative analysis of tobacco additives in cigarettes.},
  author={Careen Merckel and Fritz Pragst and Astrid Ratzinger and Beat Aebi and Werner Bernhard and Frank Sporkert},
  journal={Journal of chromatography. A},
  year={2006},
  volume={1116 1-2},
  pages={10-9}
}
Cigarettes may contain up to 10% by weight additives which are intended to make them more attractive. A fast and rugged method for a cigarette-screening for additives with medium volatility was developed using automatic headspace solid phase microextraction (HS-SPME) with a 65 microm carbowax-divinylbenzene fiber and gas chromatography-mass spectrometry (GC-MS) with standard electron impact ionisation. In three runs, each cigarette sample was extracted in closed headspace vials using basic… CONTINUE READING