Application of complementary mass spectrometric techniques to the identification of ketoprofen phototransformation products.

@article{Kosjek2011ApplicationOC,
  title={Application of complementary mass spectrometric techniques to the identification of ketoprofen phototransformation products.},
  author={Tina Kosjek and Silva Perko and Ester Heath and Bogdan Kralj and Du{\vs}an Žigon},
  journal={Journal of mass spectrometry : JMS},
  year={2011},
  volume={46 4},
  pages={391-401}
}
Ketoprofen (KP) is a nonsteroidal anti-inflammatory drug, which during UV irradiation rapidly transforms into benzophenone derivatives. Such transformation products may occur after topical application of KP, which is then exposed to sunlight resulting in a photo-allergic reaction. These reactions are mediated by the benzophenone moiety independently of the amount of allergen. The same reactions will also occur during wastewater or drinking water treatment albeit their effect in the aqueous… CONTINUE READING

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