Application of circulating plasma/serum EBV DNA in the clinical management of nasopharyngeal carcinoma.

@article{Yip2014ApplicationOC,
  title={Application of circulating plasma/serum EBV DNA in the clinical management of nasopharyngeal carcinoma.},
  author={Timothy Tak-Chun Yip and Roger Kai-cheong Ngan and Alvin H. W. Fong and Stephen C. K. Law},
  journal={Oral oncology},
  year={2014},
  volume={50 6},
  pages={527-38}
}
Elevated levels of circulating cell-free Epstein-Barr virus (EBV) DNA have been detected in plasma and serum samples from nasopharyngeal cancer (NPC) patients by quantitative real time PCR (qPCR) test. This qPCR test for circulating EBV DNA was found to be useful in the clinical management of NPC patients. For instance, EBV DNA qPCR test has good sensitivity and specificity in the detection of NPC at disease onset. Increase of the viral DNA load was found in NPC patients at late stages of… CONTINUE READING

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