Application of canaloplasty in glaucoma gene therapy: where are we?

Abstract

PURPOSE Schlemm's canal (SC) inner wall is adjacent to the juxtacanalicular trabecular meshwork (TM) over their entire circumference. We seek to transfer reporter and therapeutic genes to these outflow-modulating tissues via canaloplasty surgery in live monkeys. METHODS A standard canaloplasty surgical approach was performed in cynomolgus monkeys using… (More)
DOI: 10.1089/jop.2013.0203

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