Application of boron-entrapped stealth liposomes to inhibition of growth of tumour cells in the in vivo boron neutron-capture therapy model.

@article{Yanagie2006ApplicationOB,
  title={Application of boron-entrapped stealth liposomes to inhibition of growth of tumour cells in the in vivo boron neutron-capture therapy model.},
  author={Hironobu Yanagie and Kazuo Maruyama and Tomoko Takizawa and Osamu Ishida and Koichi Ogura and Takuya Matsumoto and Yuriko Sakurai and Tooru Kobayashi and Atsuko Shinohara and J. J. Rant and Jure Skvarc and Radovan D Ili{\'c} and Guido Kuhne and M. Inanobe Chiba and Yoshitaka Furuya and Hirotaka Sugiyama and Tomoyuki Hisa and Koji Ono and Hisao Kobayashi and Masazumi Eriguchi},
  journal={Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie},
  year={2006},
  volume={60 1},
  pages={43-50}
}
Tumour cell destruction in boron neutron-capture therapy (BNCT) is due to the nuclear reaction between (10)B and thermal neutrons. It is necessary for effective BNCT therapy to accumulate (10)B atoms in the tumour cells. The delivery system consisted of polyethylene-glycol (PEG) binding liposomes (DPPC/cholesterol/DSPC-PEG2000) with an entrapped (10)B… CONTINUE READING