Application of bicellar systems on skin: diffusion and molecular organization effects.

  title={Application of bicellar systems on skin: diffusion and molecular organization effects.},
  author={G. Rodr{\'i}guez and L. Rubio and M. Cocera and J. Estelrich and R. Pons and A. de la Maza and O. L{\'o}pez},
  journal={Langmuir : the ACS journal of surfaces and colloids},
  volume={26 13},
The effect of bicelles formed by dipalmitoylphosphatidylcholine (DPPC)/dihexanoylphosphatidylcholine (DHPC) on stratum corneum (SC) lipids was studied by attenuated total reflectance-Fourier transform infrared (ATR-FTIR) spectroscopy at different temperatures. Analysis of the lipid organization in terms of chain conformational order and lateral packing shows that the use of bicelles hampers the fluidification of SC lipids with temperature and leads to a lateral packing corresponding to a stable… Expand
A unique bicellar nanosystem combining two effects on stratum corneum lipids.
Bicellar systems to modify the phase behaviour of skin stratum corneum lipids.
Characterization of new DOPC/DHPC platform for dermal applications
Bicellar systems as new delivery strategy for topical application of flufenamic acid.
Modification of the conformational skin structure by treatment with liposomal formulations and its correlation to the penetration depth of aciclovir.
  • A. Hasanovic, R. Winkler, G. Resch, C. Valenta
  • Chemistry, Medicine
  • European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V
  • 2011
Lamellar body mimetic system: An up-to-down repairing strategy of the stratum corneum lipid structure.


European Workshop on Neutron , X - Ray and Light Scattering as an Investigative Tool for Colloidal and Polymeric Systems