Application of approximate variances of variance components and their ratios in genetic tests

@article{Dieters1995ApplicationOA,
  title={Application of approximate variances of variance components and their ratios in genetic tests},
  author={Mark J. Dieters and Timothy L. White and Ramon C. Littell and Gary R. Hodge},
  journal={Theoretical and Applied Genetics},
  year={1995},
  volume={91},
  pages={15-24}
}
The application and underlying assumptions of formulae used to estimate the variance of variance components and ratios of variance components are fully described for (1) variance components estimated using Henderson's Method 3 (HM3) and Restricted Maximum Likelihood (REML) and (2) ratios of variance components commonly used in genetic tests — biased and unbiased heritabilities. A first-order Taylor series approximation is often used to estimate the variance of a ratio of two random variables (e… CONTINUE READING
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