Application of antimicrobial polypeptide host defenses to aquaculture: Exploitation of downregulation and upregulation responses.

@article{Noga2011ApplicationOA,
  title={Application of antimicrobial polypeptide host defenses to aquaculture: Exploitation of downregulation and upregulation responses.},
  author={Edward J. Noga and Anirudh J. Ullal and Jone Corrales and Jorge Manuel de Oliveira Fernandes},
  journal={Comparative biochemistry and physiology. Part D, Genomics & proteomics},
  year={2011},
  volume={6 1},
  pages={44-54}
}
Antimicrobial polypeptides (AMPPs), consisting of peptides and small proteins with antimicrobial activity, are an integral component of innate immunity. Their often potent properties and widespread prevalence in fish suggests that designing means of manipulating their levels has considerable potential for maintaining or improving fish health. There is evidence that a number of chronic stresses lead to significant downregulation of AMPPs and thus their monitoring could be a highly sensitive… CONTINUE READING