Application of a simple and sensitive GC-MS method for determination of morphine in the hair of opium abusers.

@article{Sabzevari2004ApplicationOA,
  title={Application of a simple and sensitive GC-MS method for determination of morphine in the hair of opium abusers.},
  author={Omid Sabzevari and Kh Abdi and Mohammad Amini and Abbas Shafiee},
  journal={Analytical and bioanalytical chemistry},
  year={2004},
  volume={379 1},
  pages={120-4}
}
Thirty hair samples were collected from male opioid abusers for whom the presence of morphine in their urine samples was confirmed by thin layer chromatography (TLC). The hair samples were decontaminated by washing with isopropanol, deionized water, and isopropanol, dried at room temperature, and cut into small pieces. Samples of the latter (30 mg ) were digested by incubation in a mixture of methanol-trifluoroacetic acid (9:1) for 18 h at 45 degrees C and sonicated to improve the extraction… CONTINUE READING