Application of a novel analysis to measure the binding of the membrane-translocating peptide penetratin to negatively charged liposomes.

@article{Persson2003ApplicationOA,
  title={Application of a novel analysis to measure the binding of the membrane-translocating peptide penetratin to negatively charged liposomes.},
  author={Daniel Persson and Per E G Thor{\'e}n and Mattias Herner and Per Lincoln and B. Nelson Norden},
  journal={Biochemistry},
  year={2003},
  volume={42 2},
  pages={421-9}
}
The binding of penetratin, a peptide that has been found useful for cellular delivery of large hydrophilic molecules, to negatively charged vesicles was investigated. The surface charge density of the vesicles was varied by mixing zwitterionic dioleoylphosphatidylcholine (DOPC) and negatively charged dioleoylphosphatidylglycerol (DOPG) at various molar… CONTINUE READING