Application of a new molecular technique for the genetic evaluation of products of conception.

@article{Grati2013ApplicationOA,
  title={Application of a new molecular technique for the genetic evaluation of products of conception.},
  author={Francesca Romana Grati and Denise Molina Gomes and Devika Ganesamoorthy and Livia Marcato and Simona De Toffol and El{\'e}onore Blondeel and Francesca Malvestiti and Laurence Loeuillet and A. Ruggeri and Robert Wainer and Federico Maggi and Azzedine Aboura and C{\'e}line Dupont and Anne Claude Tabet and Fabien Guimiot and Howard Robert Slater and Giuseppe Simoni and Francois Vialard},
  journal={Prenatal diagnosis},
  year={2013},
  volume={33 1},
  pages={
          32-41
        }
}
OBJECTIVES Karyotyping is a well-established method of investigating the genetic content of product of conceptions (POCs). Because of the high rate of culture failure and maternal cell contamination, failed results or 46,XX findings are often obtained. Different molecular approaches that are not culture dependent have been proposed to circumvent these limits. On the basis of the robust experience previously obtained with bacterial artificial chromosomes (BACs)-on-Beads™ (BoBs™), we evaluated… CONTINUE READING
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