Application of a fiber-matrix model to transport in renal tubules

  title={Application of a fiber-matrix model to transport in renal tubules},
  author={W. D. Fraser and Andrew D. Baines},
  journal={The Journal of General Physiology},
  pages={863 - 879}
The effects of tight junction structure on water and solute fluxes across proximal tubular epithelium were examined with fiber-matrix equations previously derived by Curry and Michel (1980. Microvascular Research. 20:96-99). Using plausible estimates of tight junction fiber length and width the model predicts solute (Ps) and water permeability (Lp) coefficients that agree with the measured values. When fiber-matrix and pore models were compared for physiologically relevant ranges of matrix void… CONTINUE READING


Publications citing this paper.


Publications referenced by this paper.
Showing 1-10 of 21 references

Fluid flow through granular beds

  • P. C. Carman
  • Transactions of the Institute of Chemical…
  • 1937
Highly Influential
1 Excerpt

Mechanics and thermodynamics of transcapillary exchange

  • F. E. Curry
  • Handbook of Physiology . Section 2 . Vol . IV…
  • 1984
1 Excerpt

Localization of the regulatory subunit of type lI cyclic AMP - dependent protein kinase on the cytoplasmic microtubule of cultured cells

  • A. Steiner
  • Cell Biology International Reports .
  • 1982

Water flow through a fiber matrix of hyaluronic acid

  • J. L. Anderson
  • Microvascular Research .
  • 1982

Transport of water and solutes across capillary endothelium

  • G. Giebisch
  • Transport Organs .
  • 1979

Similar Papers

Loading similar papers…