Application of SVM to predict membrane protein types.

  title={Application of SVM to predict membrane protein types.},
  author={Yu Dong Cai and Pong-Wong Ricardo and Chih-Hung Jen and Kuo-Chen Chou},
  journal={Journal of theoretical biology},
  volume={226 4},
As a continuous effort to develop automated methods for predicting membrane protein types that was initiated by Chou and Elrod (PROTEINS: Structure, Function, and Genetics, 1999, 34, 137-153), the support vector machine (SVM) is introduced. Results obtained through re-substitution, jackknife, and independent data set tests, respectively, have indicated that the SVM approach is quite a promising one, suggesting that the covariant discriminant algorithm (Chou and Elrod, Protein Eng. 12 (1999) 107… CONTINUE READING

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