Application of SSH and a macroarray to investigate altered gene expression in Mytilus edulis in response to exposure to benzo[a]pyrene.

@article{Brown2006ApplicationOS,
  title={Application of SSH and a macroarray to investigate altered gene expression in Mytilus edulis in response to exposure to benzo[a]pyrene.},
  author={Margaret M Brown and Ian M. Davies and Colin F. Moffat and John A. Craft},
  journal={Marine environmental research},
  year={2006},
  volume={62 Suppl},
  pages={S128-35}
}
The lack of genomic resources for aquatic invertebrates restricts their use as sentinel species in coastal environments. It is known that where genomic data are not available, suppression subtractive hybridisation (SSH) can generate cDNA libraries representative of pollutant-responsive gene transcription in aquatic vertebrates. To assess whether the approach was equally suited to aquatic invertebrates, altered gene expression in digestive gland of the mussel, Mytilus edulis, in response to… CONTINUE READING
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