Application of Lumping Analysis in Modelling the Living Systems – A Trade-off Between Simplicity and Model Quality

Abstract

General chemical engineering modelling principles are valuable tools to represent both stationary and dynamic characteristics of complex cell processes. Elaboration of reduced (lumped) dynamic models uses all types of information ‘translated’ from the ‘language’ of molecular biology to that of mechanistical chemistry, by preserving cell structural hierarchy… (More)

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