Application of Information Technology: The Shared Health Research Information Network (SHRINE): A Prototype Federated Query Tool for Clinical Data Repositories

@article{Weber2009ApplicationOI,
  title={Application of Information Technology: The Shared Health Research Information Network (SHRINE): A Prototype Federated Query Tool for Clinical Data Repositories},
  author={Griffin M. Weber and Shawn N. Murphy and Andrew J. McMurry and Douglas MacFadden and Daniel J. Nigrin and Susanne E. Churchill and Isaac S. Kohane},
  journal={Journal of the American Medical Informatics Association : JAMIA},
  year={2009},
  volume={16 5},
  pages={624-30}
}
The authors developed a prototype Shared Health Research Information Network (SHRINE) to identify the technical, regulatory, and political challenges of creating a federated query tool for clinical data repositories. Separate Institutional Review Boards (IRBs) at Harvard's three largest affiliated health centers approved use of their data, and the Harvard Medical School IRB approved building a Query Aggregator Interface that can simultaneously send queries to each hospital and display aggregate… CONTINUE READING
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