Application of High-Density DNA Resequencing Microarray for Detection and Characterization of Botulinum Neurotoxin-Producing Clostridia

@inproceedings{Vanhomwegen2013ApplicationOH,
  title={Application of High-Density DNA Resequencing Microarray for Detection and Characterization of Botulinum Neurotoxin-Producing Clostridia},
  author={Jessica Vanhomwegen and Nicolas Berthet and Christelle Mazuet and Ghislaine Guigon and Tatiana Vallaeys and Rayna Stamboliyska and Philippe Dubois and Giulia C. Kennedy and Stewart T Cole and Val{\'e}rie Caro and Jean-Claude Manuguerra and Michel R Popoff},
  booktitle={PloS one},
  year={2013}
}
BACKGROUND Clostridium botulinum and related clostridia express extremely potent toxins known as botulinum neurotoxins (BoNTs) that cause severe, potentially lethal intoxications in humans. These BoNT-producing bacteria are categorized in seven major toxinotypes (A through G) and several subtypes. The high diversity in nucleotide sequence and genetic organization of the gene cluster encoding the BoNT components poses a great challenge for the screening and characterization of BoNT-producing… CONTINUE READING

Similar Papers

Citations

Publications citing this paper.
SHOWING 1-8 OF 8 CITATIONS

A penicillin- and metronidazole-resistant Clostridium botulinum strain responsible for an infant botulism case.

  • Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases
  • 2016

References

Publications referenced by this paper.
SHOWING 1-10 OF 60 REFERENCES

[Botulinum toxin as a biological weapon].

  • Duodecim; laaketieteellinen aikakauskirja
  • 2012
VIEW 1 EXCERPT

An outbreak of food - borne botulism in Scotland , United Kingdom , November 2011

JM Pingeon, C Vanbockstael, MR Popoff, LA King, B Deschamps
  • Euro Surveill
  • 2011

An outbreak of food-borne botulism in Scotland, United Kingdom, November 2011.

  • Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin
  • 2011

Clostridium botulinum. Genomes of Foodborne and Waterborne Pathogens

H Brüggemann, A Woller, C Mazuet, MR Popoff
  • 2011
VIEW 1 EXCERPT