Application of FTIR microspectroscopy for characterization of biomolecular changes in human melanoma cells treated by sesamol and kojic acid.

@article{Srisayam2014ApplicationOF,
  title={Application of FTIR microspectroscopy for characterization of biomolecular changes in human melanoma cells treated by sesamol and kojic acid.},
  author={Montra Srisayam and Natthida Weerapreeyakul and Sahapat Barusrux and Waraporn Tanthanuch and Kanjana Thumanu},
  journal={Journal of dermatological science},
  year={2014},
  volume={73 3},
  pages={241-50}
}
BACKGROUND Hyperpigmentation is aesthetic undesirable. Sesamol and the standard antimelanogenic agent (kojic acid) were shown to hinder melanogenesis by blocking tyrosinase and reducing melanin content. OBJECTIVE The FTIR microspectroscopy was used in an attempt to find a novel method to define biological alternation in a melanogenesis inhibition of sesamol and kojic acid. METHODS Tyrosinase inhibition and melanin content of sesamol and kojic acid were evaluated. The FTIR microspectroscopy… CONTINUE READING
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