Application of DNA chip techniques for Yq microdeletion analysis in infertile males

  title={Application of DNA chip techniques for Yq microdeletion analysis in infertile males},
  author={Suman Lee and Hyun Suk Joo and S H Lee and Jung Eun Park and Jong Man Kim and Jae Hoon Hwang and Key Seung Cho and Seung Yong Hwang},
  journal={Experimental & Molecular Medicine},
Our aim was to apply DNA chip technology as a diagnostic tool in infertility research and clinics. Six loci, including a sex-determining region on the Y chromosome and five sequence-tagged sites in azoospermia-factor regions were investigated in infertile male patients. Our method produced a sensitive signal, which showed the presence or absence of the STS regions on the Y chromosome. The results from 93 patients with non- obstructive azoospermia, oligoathenoteratozoospermia, or oligozoospermia… CONTINUE READING
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