Application of CD27 as a marker for distinguishing human NK cell subsets.

It has long been recognized that human NK cells can be divided into two phenotypically and functionally distinct subsets, based on their levels of expression of CD56. We recently found that CD27 distinguishes subsets of mature mouse NK cells. Here we report that CD27 can be used as a marker to discriminate human NK cell subsets. The majority of peripheral… (More)