Application of Anticancer Agents from Fermentation of Soy Using Bifidobacterium and Lactobacillus Sp., A Review
@inproceedings{Rani2014ApplicationOA, title={Application of Anticancer Agents from Fermentation of Soy Using Bifidobacterium and Lactobacillus Sp., A Review}, author={V. Usha Rani and B V Pradeep}, year={2014} }
Cancer drug development presently focuses on rational drugs that have the ability to cross the cell membrane and bind to a specific enzyme or receptor. Current research in cancer treatment aimed at finding new prognostic targets for therapy, the goal of research is to find natural substances that modulate the regulatory signals such as cell cycle, growth factor and cell death. Soybean (Glycine max. L.) a common part of diet possess a high content of proteins and important source of…
5 Citations
Ethyl acetate subfractions from ethanol extracts of fermented oats (Avena sativa L.) exert anti-cancer properties in vitro and in vivo through G2/M and S Phase arrest and apoptosis
- BiologyJournal of Cancer
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EASs exhibited anti-cancer activities in vitro and in vivo via cell cycle arrest and apoptosis, suggesting that polyphenol-enriched composition from fermented oats might become a promising candidate for impeding the development and progression of liver cancer.
Bifidobacterium sp as Probiotic Agent - Roles and Applications
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Bifidobacteria can be considered as a probiotic and it plays an important role in anticholesterolemic, lactose intolerance, anticancerogenic, immunomodulatory effects etc.
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Lactobacillus and Bifidobacterium are capable of hydrolyzing glycosidic bond of glycosidic isoflavone in soy extract (milk) during microbial fermentation. Each strain has proved enzymatic ability in…
References
SHOWING 1-10 OF 40 REFERENCES
Molecular effects of the isoflavonoid genistein in prostate cancer.
- BiologyClinical prostate cancer
- 2005
The mechanism of action of genistein is complex and includes several cellular pathways, and it arrests the cell cycle, induces apoptosis, and has antiangiogenic and antimetastatic properties and antioxidant activity.
Antiproliferative effects of isoflavones on human cancer cell lines established from the gastrointestinal tract.
- Biology, ChemistryCancer research
- 1993
The results suggest that two of isoflavone derivatives, biochanin A and genistein, inhibit the cell growth of stomach cancer cell lines in vitro through activation of a signal transduction pathway for apoptosis, and in vivo experiments demonstrate that biochan in A can be used as an anticancer agent.
Genistein inhibits both estrogen and growth factor-stimulated proliferation of human breast cancer cells.
- BiologyCell growth & differentiation : the molecular biology journal of the American Association for Cancer Research
- 1996
Although genistein inhibits the growth of breast cancer cells in culture, it does so without gross inhibition of PTK activity, suggesting that in vivo, breast cancer growth is regulated by estrogens and peptide growth factors.
Enrichment of Genistein in Soy Protein Concentrate with b‐glucosidase
- Chemistry
- 2000
:
Genistein has been reported to have the most potent anticarcinogenic effect among isoflavones. Conversion of genistin in the glucoside form to genistein in the aglucone form by a b-glucosidase…
Effects of daidzein on estrogen-receptor-positive and negative pancreatic cancer cells in vitro.
- Biology, MedicineWorld journal of gastroenterology
- 2004
Daidzein has antiproliferative effects on human estrogen-receptor-positive and negative pancreatic cancer cells, but their mechanisms may be different.
Effect of dietary genistein on antioxidant enzyme activities in SENCAR mice.
- BiologyNutrition and cancer
- 1996
The results suggest that dietarygenistein enhances the activities of antioxidant enzymes in various organs, which may be a mechanism(s) of genistein's chemopreventive action.
Does high soy milk intake reduce prostate cancer incidence? The Adventist Health Study (United States)
- MedicineCancer Causes & Control
- 2004
Frequent consumption of soy milk was associated with 70 per cent reduction of the risk of prostate cancer and the association was upheld when extensive adjustments were performed.
Isoflavone aglycone-rich extract without soy protein attenuates atherosclerosis development in cholesterol-fed rabbits.
- Chemistry, MedicineThe Journal of nutrition
- 2000
It is suggested that the antioxidative action of isoflavones and their antioxidative metabolites inhibit the oxidation of LDL, thereby exerting an antiatherosclerotic effect.
Daidzein causes cell cycle arrest at the G1 and G2/M phases in human breast cancer MCF-7 and MDA-MB-453 cells.
- Biology, ChemistryPhytomedicine : international journal of phytotherapy and phytopharmacology
- 2008
Genistein, a specific inhibitor of tyrosine-specific protein kinases.
- Biology, Computer ScienceThe Journal of biological chemistry
- 1987