Application of 13C NMR cross-polarization inversion recovery experiments for the analysis of solid dosage forms.


Solid-state nuclear magnetic resonance (ssNMR) is a powerful and unique method for analyzing solid forms of the active pharmaceutical ingredients (APIs) directly in their original formulations. Unfortunately, despite their wide range of application, the ssNMR experiments often suffer from low sensitivity and peaks overlapping between API and excipients. To… (More)
DOI: 10.1016/j.ijpharm.2016.09.066