Applicability of the principles of developmental pharmacology to the study of environmental toxicants.

@article{McCarver2004ApplicabilityOT,
  title={Applicability of the principles of developmental pharmacology to the study of environmental toxicants.},
  author={D. Gail McCarver},
  journal={Pediatrics},
  year={2004},
  volume={113 4 Suppl},
  pages={969-72}
}
Although nontherapeutic xenobiotics represent the vast majority of environmental exposures during childhood, study of these compounds in children has lagged behind drug studies. Some useful extrapolation can be made from the latter, however. An increased impetus for pediatric pharmacology studies resulted from evidence of shortcomings in algorithmic approaches to dosing and the recognition of differing efficacy and toxicity in children compared with adults. With some drugs, developmental… CONTINUE READING

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