Applicability of Near-Infrared Spectroscopy to Measure Cerebral Autoregulation Noninvasively in Neonates: A Validation Study in Piglets

@article{Hahn2011ApplicabilityON,
  title={Applicability of Near-Infrared Spectroscopy to Measure Cerebral Autoregulation Noninvasively in Neonates: A Validation Study in Piglets},
  author={Gitte H. Hahn and Christian Heiring and Ole Pryds and Gorm Greisen},
  journal={Pediatric Research},
  year={2011},
  volume={70},
  pages={166-170}
}
Impaired cerebral autoregulation (CA) is common and is associated with brain damage in sick neonates. Frequency analysis using spontaneous changes in arterial blood pressure (ABP) and cerebral near-infrared spectroscopy (NIRS) has been used to measure CA in several clinical studies. Coherence of the NIRS and ABP signals (i.e. correlation in the frequency domain) detects impairment of CA, whereas gain (i.e. magnitude of ABP variability passing from systemic to cerebral circulation) estimates the… CONTINUE READING