Appendectomy for Therapy-Refractory Ulcerative Colitis Results in Pathological Improvement of Colonic Inflammation: Short-Term Results of the PASSION Study

@article{Sahami2019AppendectomyFT,
  title={Appendectomy for Therapy-Refractory Ulcerative Colitis Results in Pathological Improvement of Colonic Inflammation: Short-Term Results of the PASSION Study},
  author={Saloomeh Sahami and Manon E. Wildenberg and Lianne Koens and Glen Doherty and Solenne Martin and G. R. A. M. D'Haens and G Cullen and W. A. Bemelman and Desmond C. Winter and Christianne Buskens},
  journal={Journal of Crohn's and Colitis},
  year={2019},
  volume={13},
  pages={165–171}
}
  • Saloomeh Sahami, Manon E. Wildenberg, +7 authors Christianne Buskens
  • Published in Journal of Crohn's & colitis 2019
  • Medicine
  • Background and Aims The objective of this study was to examine the modulating effect of an appendectomy on the disease course of therapy-refractory ulcerative colitis [UC] patients, and to analyse appendiceal pathological characteristics predictive of pathological response. Methods Patients with therapy-refractory UC, and referred for proctocolectomy, were invited to undergo laparoscopic appendectomy first. The primary end points were clinical response after 3 and 12 months. Secondary end… CONTINUE READING

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