Appendectomy and the development of ulcerative colitis: results of a metaanalysis of published case-control studies

@article{Koutroubakis2000AppendectomyAT,
  title={Appendectomy and the development of ulcerative colitis: results of a metaanalysis of published case-control studies},
  author={Ioannis E. Koutroubakis and Ioannis G Vlachonikolis},
  journal={American Journal of Gastroenterology},
  year={2000},
  volume={95},
  pages={171-176}
}
OBJECTIVE:Numerous epidemiological studies have been performed to determine risk factors that might contribute to the development of ulcerative colitis (UC). Recent studies have focused on the role of appendectomy in the disease's pathogenesis. This report aims to review and analyze the degree of evidence from recent published studies.METHODS:Medline and Embase databases were scrutinized for studies published between 1987 and January 1999. Reference lists from published articles, reviews, and… CONTINUE READING