Appearance of insulin-like growth factor mRNA in the liver and pyloric ceca of a teleost in response to exogenous growth hormone.

@article{Shamblott1995AppearanceOI,
  title={Appearance of insulin-like growth factor mRNA in the liver and pyloric ceca of a teleost in response to exogenous growth hormone.},
  author={M. Shamblott and C. Cheng and D. Bolt and T. T. Chen},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1995},
  volume={92 15},
  pages={
          6943-6
        }
}
  • M. Shamblott, C. Cheng, +1 author T. T. Chen
  • Published 1995
  • Biology, Medicine
  • Proceedings of the National Academy of Sciences of the United States of America
Augmentation of vertebrate growth by growth hormone (GH) is primarily due to its regulation of insulin-like growth factor I (IGF I) and IGF II levels. To characterize the effect of GH on the levels of IGF I and IGF II mRNA in a teleost, 10 micrograms of bovine GH (bGH) per g of body weight was administered to juvenile rainbow trout (Oncorhynchus mykiss) through i.p. injection. The levels of IGF I and IGF II mRNA were determined simultaneously, by using RNase protection assays, in the liver… Expand
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