Apparent diffusion coefficient as an MR imaging biomarker of low-risk ductal carcinoma in situ: a pilot study.

  title={Apparent diffusion coefficient as an MR imaging biomarker of low-risk ductal carcinoma in situ: a pilot study.},
  author={Mami Iima and Denis Le Bihan and Ryosuke Okumura and T Okada and Koji Fujimoto and Shotaro Kanao and Shiro Tanaka and Masakazu Fujimoto and Hiromi Sakashita and Kaori Togashi},
  volume={260 2},
PURPOSE To evaluate the potential of apparent diffusion coefficients (ADCs) obtained at quantitative diffusion-weighted magnetic resonance (MR) imaging of the breast as a biomarker of low-grade ductal carcinoma in situ (DCIS). MATERIALS AND METHODS This retrospective study was approved by an institutional review board, and the requirement to obtain informed consent was waived. Twenty-two women (age range, 36-75 years; mean age, 56.4 years) with pure DCIS (seven with low-grade DCIS, five with… CONTINUE READING


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