Apparent apoptotic cell death in the olfactory epithelium of adult rodents: death occurs at different developmental stages.

@article{Mahalik1996ApparentAC,
  title={Apparent apoptotic cell death in the olfactory epithelium of adult rodents: death occurs at different developmental stages.},
  author={Thomas J. Mahalik},
  journal={The Journal of comparative neurology},
  year={1996},
  volume={372 3},
  pages={
          457-64
        }
}
In the olfactory epithelium of adult rodent, receptor neurons are generated continually. Despite the ongoing generation of new neurons, no corresponding increase occurs in the thickness of the mature olfactory epithelium. Thus, epithelial cell death must occur to offset the continual generation of new cells. In the present study, a sensitive method to label nicked DNA in dying cells was combined with immunocytochemistry to determine the identity of dying olfactory cells. In addition, the… CONTINUE READING

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