Apoptotic mechanisms of N1-acetylacetone, N4-4-methoxy-salicylidene-thiosemicarbazide chelating with Nickel(II) on HL60 leukemia cells.

@article{Kaya2016ApoptoticMO,
  title={Apoptotic mechanisms of N1-acetylacetone, N4-4-methoxy-salicylidene-thiosemicarbazide chelating with Nickel(II) on HL60 leukemia cells.},
  author={B{\"u}şra Kaya and Belkis Atasever-Arslan and Zeynep Kalkan and Hazal G{\"u}r and Bahri {\"U}lk{\"u}seven},
  journal={General physiology and biophysics},
  year={2016},
  volume={35 4},
  pages={451-458}
}
Thiosemicarbozone complexes that have a broad spectrum of biological activity are formed as a result of condensation reaction between thiosemicarbazide [H2N(C=S)-NH-NH2] and carbonyl-containing compounds. A new Nickel(II) complexes with N1-acetylacetone, N4-4-methoxy-salicylidene-thiosemicarbazidato ligand was synthesized and characterized. We studied the… CONTINUE READING