Apoptotic events induced by synthetic naphthylchalcones in human acute leukemia cell lines.

@article{Maioral2013ApoptoticEI,
  title={Apoptotic events induced by synthetic naphthylchalcones in human acute leukemia cell lines.},
  author={Mariana Franzoni Maioral and P{\^a}mela Cristina Gaspar and Gabriela Regina Rosa Souza and Alessandra Mascarello and Louise Domeneghini Chiaradia and Marley Aparecida Lic{\'i}nio and Ana Carolina Rabello de Moraes and Rosendo Augusto Yunes and Ricardo Jos{\'e} Nunes and Maria Cl{\'a}udia Santos-Silva},
  journal={Biochimie},
  year={2013},
  volume={95 4},
  pages={866-74}
}
Acute leukemia is a disorder of the hematopoietic system characterized by the expansion of a clonal population of cells blocked from differentiating into mature cells. Recent studies have shown that chalcones and their derivatives induce apoptosis in different cell lines. Since new compounds with biological activity are needed, the aim of this study was to… CONTINUE READING