Apoptotic endothelial cells demonstrate increased adhesiveness for human mesenchymal stem cells.

@article{Potapova2009ApoptoticEC,
  title={Apoptotic endothelial cells demonstrate increased adhesiveness for human mesenchymal stem cells.},
  author={Irina A. Potapova and Ira S. Cohen and Sergey V. Doronin},
  journal={Journal of cellular physiology},
  year={2009},
  volume={219 1},
  pages={23-30}
}
Mesenchymal stem cells (MSCs) participate in the wound healing process in mammalians. Adhesion of MSCs to endothelium is a key step in the homing of MSCs circulating in the bloodstream to the sites of injury and inflammation. Because endothelial cells (ECs) may become apoptotic under certain pro-inflammatory conditions, we investigated the effects of pro-inflammatory, TNF-alpha and IL-1 beta, and pro-apoptotic agents, actinomycin D, cycloheximide, okadaic acid, wortmannin, and staurosporine, on… CONTINUE READING
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