Apoptotic cells can induce compensatory cell proliferation through the JNK and the Wingless signaling pathways.

@article{Ryoo2004ApoptoticCC,
  title={Apoptotic cells can induce compensatory cell proliferation through the JNK and the Wingless signaling pathways.},
  author={Hyung Don Ryoo and Travis Gorenc and Hermann Steller},
  journal={Developmental cell},
  year={2004},
  volume={7 4},
  pages={
          491-501
        }
}
In many metazoans, damaged and potentially dangerous cells are rapidly eliminated by apoptosis. In Drosophila, this is often compensated for by extraproliferation of neighboring cells, which allows the organism to tolerate considerable cell death without compromising development and body size. Despite its importance, the mechanistic basis of such compensatory proliferation remains poorly understood. Here, we show that apoptotic cells express the secretory factors wingless (wg) and… Expand
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