Apoptotic cell removal

  title={Apoptotic cell removal},
  author={Peter M Henson and Donna L. Bratton and Valerie Fadok},
  journal={Current Biology},
Ingestion by professional or amateur phagocytes is the fate of most cells that undergo apoptosis. Studies in both Caenorhabditis elegans and mammals are now converging to reveal some of the key mechanisms and consequences of this removal process. At least seven corpse removal genes in nematodes have mammalian equivalents, and represent elements of signaling pathways involved in uptake. In mammals, a wide variety of apoptotic cell recognition receptors has been implicated and appears to be… CONTINUE READING
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