Apoptotic cell death under hypoxia.

@article{Sendoel2014ApoptoticCD,
  title={Apoptotic cell death under hypoxia.},
  author={Ataman Sendoel and Michael O. Hengartner},
  journal={Physiology},
  year={2014},
  volume={29 3},
  pages={
          168-76
        }
}
Eukaryotic life depends largely on molecular oxygen. During evolution, ingenious mechanisms have evolved that allow organisms to adapt when oxygen levels decrease. Many of these adaptional responses to low oxygen are orchestrated by the heterodimeric transcription factor hypoxia-inducible factor (HIF). Here, we review the link between HIF and apoptosis. 
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