Apoptotic cell death induced by optic nerve lesion in the neonatal rat.

@article{Rabacchi1994ApoptoticCD,
  title={Apoptotic cell death induced by optic nerve lesion in the neonatal rat.},
  author={Sylvia A Rabacchi and Luca Bonfanti and Xiu Hua Liu and Lamberto Maffei},
  journal={The Journal of neuroscience : the official journal of the Society for Neuroscience},
  year={1994},
  volume={14 9},
  pages={
          5292-301
        }
}
Cell death can be ascribed to one of two distinct modes of degeneration: apoptosis (programmed or active cell death) or necrosis (passive degeneration). While apoptosis is generally assumed to occur in physiological conditions such as normal development or tissue turnover, necrotic cell degeneration is induced in pathological situations. Here we report that also in a pathological situation, such as after axotomy in the CNS, apoptotic type of cell death comes into play: following intracranial… CONTINUE READING
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