Apoptotic and proliferation indexes in primary superficial bladder tumors.

  title={Apoptotic and proliferation indexes in primary superficial bladder tumors.},
  author={Ricardo Gonz{\'a}lez-C{\'a}mpora and Guillermo Davalos-Casanova and Antonio Beato-Moreno and Rafael Jes{\'u}s Luque and Jose Alvarez-Kindel{\'a}n and Mar{\'i}a Jos{\'e} Requena and Rodolfo Montironi and Antonio Lopez-Beltran},
  journal={Cancer letters},
  volume={242 2},
Whether apoptotic index [AI] and/or Ki-67 labeling index [Ki-67LI] add prognostic information in bladder cancer remains unclear. Mean AI and Ki-67 LI increased with grade and stage in 147 superficial bladder tumors. AI (>1.7%) correlated with tumor size, grade and proliferation. Ki-67 LI (>10%) correlated with higher grade and stage. Tumor size and Ki-67 LI were independent predictors of disease-free and progression-free survival, respectively. Tumor size, patient's age and tumor's recurrence… CONTINUE READING