Apoptotic activity of caged xanthones from Garcinia hanburyi in cholangiocarcinoma cell lines.

@article{Hahnvajanawong2010ApoptoticAO,
  title={Apoptotic activity of caged xanthones from Garcinia hanburyi in cholangiocarcinoma cell lines.},
  author={Chariya Hahnvajanawong and Wongwarut Boonyanugomol and Tapanawan Nasomyon and Watcharin Loilome and Nisana Namwat and Natthinee Anantachoke and Wichittra Tassaneeyakul and Banchob Sripa and Wises Namwat and Vichai Reutrakul},
  journal={World journal of gastroenterology},
  year={2010},
  volume={16 18},
  pages={2235-43}
}
AIM To investigate the growth inhibitory mechanism of four caged xanthones from Garcinia hanburyi in cholangiocarcinoma (CCA) KKU-100 and KKU-M156 cells. METHODS Four caged xanthones, selected on the basis of their anticancer potency and chemical structure diversities (i.e. isomorellin, isomorellinol, forbesione and gambogic acid) were used in this study. Growth inhibition of these caged xanthones was determined using the sulforhodamine B assay. Induction of apoptosis was assessed by… CONTINUE READING

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