Apoptotic Pathways The Roads to Ruin

@article{Green1998ApoptoticPT,
  title={Apoptotic Pathways The Roads to Ruin},
  author={D. Green},
  journal={Cell},
  year={1998},
  volume={94},
  pages={695-698}
}
  • D. Green
  • Published 1998
  • Biology, Medicine
  • Cell
Procaspase aggregation is mediated by the binding of adaptor molecules to protein interaction domains in the prodomains of some caspases. Two general types of interaction domains have been identified. Procas-pases-8 and-10 each contain two tandem death effector domains (DEDs), while procaspases-1,-2,-4,-5, and-9 Introduction contain caspase recruitment domains (CARDs). In each Nearly all physiological cell deaths in animals proceed case, the procaspases bind to adaptor molecules con-by the… Expand
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