Apoptotic Effects of Chrysin in Human Cancer Cell Lines

  title={Apoptotic Effects of Chrysin in Human Cancer Cell Lines},
  author={Boon Yin Khoo and Siang Ling Chua and Prabha Balaram},
  booktitle={International journal of molecular sciences},
Chrysin is a natural flavonoid currently under investigation due to its important biological anti-cancer properties. In most of the cancer cells tested, chrysin has shown to inhibit proliferation and induce apoptosis, and is more potent than other tested flavonoids in leukemia cells, where chrysin is likely to act via activation of caspases and inactivation of Akt signaling in the cells. Moreover, structure-activity relationships have revealed that the chemical structure of chrysin meets the… CONTINUE READING