Apoptotic Effect of Lead Acetate on Mice Astrocytes

  title={Apoptotic Effect of Lead Acetate on Mice Astrocytes},
  author={Jiang Jun-jun},
Objective To study lead acetate induced apoptosis of mice astrocytes C8 and provide theoretical criteria for the damage of lead to blood-brain barrier.Methods Mice astrocytes C8 in logarithmic growth phase were exposed to different concentration of lead acetate(0,5,10,20,and 40μmol/L) for different time periods(6,12,24,and 48 h).Proliferation of cells was detected by MTT.Cell morphology was observed by inverted phase contrast microscope.Spectrophotometer was used to detect the cell damage level… CONTINUE READING