Apoptosis-related Fas and FasL gene polymorphisms’ associations with knee osteoarthritis

  title={Apoptosis-related Fas and FasL gene polymorphisms’ associations with knee osteoarthritis},
  author={Melek Sezgin and İbrahim {\"O}mer Barlas and Seyfi Yıldır and G{\"o}zde T{\"u}rk{\"o}z and Handan Çamdeviren Ankaralı and G{\"u}nşah Şahin and Mehmet Erdal},
  journal={Rheumatology International},
To investigate the associations between Fas and FasL gene polymorphisms and susceptibility to knee osteoarthritis. Genomic DNA was obtained from 146 patients with knee osteoarthritis and 102 healthy controls. Genotype distributions and allelic frequencies of four polymorphisms of Fas (-670 G>A rs1800682, -1377 G>A rs2234767) and FasL (IVS2nt-124 A>G rs5030772, -844 T>C rs763110) genes were compared between the groups. Thereafter, this association was investigated between patients and controls… CONTINUE READING
6 Citations
40 References
Similar Papers


Publications referenced by this paper.
Showing 1-10 of 40 references

basic mechanisms

  • Hamerman D Aging, osteoarthritis
  • J Am Geriatr Soc 41:760–770 Table 3 Allelic…
  • 2013
1 Excerpt

Similar Papers

Loading similar papers…