Apoptosis-related Fas and FasL gene polymorphisms’ associations with knee osteoarthritis

@article{Sezgin2013ApoptosisrelatedFA,
  title={Apoptosis-related Fas and FasL gene polymorphisms’ associations with knee osteoarthritis},
  author={Melek Sezgin and İbrahim {\"O}mer Barlas and Seyfi Yıldır and G{\"o}zde T{\"u}rk{\"o}z and Handan Çamdeviren Ankaralı and G{\"u}nşah Şahin and Mehmet Erdal},
  journal={Rheumatology International},
  year={2013},
  volume={33},
  pages={2039-2043}
}
To investigate the associations between Fas and FasL gene polymorphisms and susceptibility to knee osteoarthritis. Genomic DNA was obtained from 146 patients with knee osteoarthritis and 102 healthy controls. Genotype distributions and allelic frequencies of four polymorphisms of Fas (-670 G>A rs1800682, -1377 G>A rs2234767) and FasL (IVS2nt-124 A>G rs5030772, -844 T>C rs763110) genes were compared between the groups. Thereafter, this association was investigated between patients and controls… CONTINUE READING
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