Apoptosis of uninfected cells induced by HIV envelope glycoproteins

@article{Ahr2004ApoptosisOU,
  title={Apoptosis of uninfected cells induced by HIV envelope glycoproteins},
  author={Barbara Ahr and Véronique Robert-Hebmann and Christian A. Devaux and Martine Biard-Piechaczyk},
  journal={Retrovirology},
  year={2004},
  volume={1},
  pages={12 - 12}
}
Apoptosis, or programmed cell death, is a key event in biologic homeostasis but is also involved in the pathogenesis of many human diseases including human immunodeficiency virus (HIV) infection. Although multiple mechanisms contribute to the gradual T cell decline that occurs in HIV-infected patients, programmed cell death of uninfected bystander T lymphocytes, including CD4+ and CD8+ T cells, is an important event leading to immunodeficiency. The HIV envelope glycoproteins (Env) play a… Expand
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