Apoptosis of supraoptic AVP neurons is involved in the development of central diabetes insipidus after hypophysectomy in rats

@article{Wang2007ApoptosisOS,
  title={Apoptosis of supraoptic AVP neurons is involved in the development of central diabetes insipidus after hypophysectomy in rats},
  author={Yihua Wang and Cui-ping Zhao and Zhigang G. Wang and Cheng-Wei Wang and Wenfeng Feng and Lijin Huang and Jialin Zhang and Songtao Qi},
  journal={BMC Neuroscience},
  year={2007},
  volume={9},
  pages={54 - 54}
}
It has been reported that various types of axonal injury of hypothalamo-neurohypophyseal tract can result in degeneration of the magnocellular neurons (MCNs) in hypothalamus and development of central diabetes insipidus (CDI). However, the mechanism of the degeneration and death of MCNs after hypophysectomy in vivo is still unclear. This present study was aimed to disclose it and to figure out the dynamic change of central diabetes insipidus after hypophysectomy. The analysis on the dynamic… CONTINUE READING

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