Apoptosis of human gastric adenocarcinoma cells induced by beta-ionone.

  title={Apoptosis of human gastric adenocarcinoma cells induced by beta-ionone.},
  author={Jia-Ren Liu and Bing-qing Chen and Bao-feng Yang and Hong-wei Dong and Chang-hao Q Sun and Qi Wang and Guo Hui Song and You-Qiang Song},
  journal={World journal of gastroenterology},
  volume={10 3},
AIM To investigate the effect of beta-ionone on the growth and apoptosis of gastric adenocarcinoma cell line SGC-7901. METHODS Using MTT, fluorescence dye (Hoechst-33258), transmission electron microscopy and the TUNEL assay, we examined growth and apoptosis of SGC-7901 cells treated with beta-ionone at various concentrations (i.e. 25, 50, 100 and 200 micromol/L) for 24 h, 48 h. RESULTS The growth of SGC-7901 cells was inhibited by beta-ionone. Seven days after treatment with beta-ionone at… CONTINUE READING